The complexity of material usage represents a big challenge in architectural and engineering design and the overcoming of that challenge is a great advantage for those who achieve it. In this Build Project you will go through the process of Shop Drawings creation for the ACM scope of work and learn how the panels are sketched. Under the supervision of an experienced industry expert, you will be able to draw details for specific conditions of the building, recommend the solutions for better material usage and choose which systems are the best for the specific design. Your Project Leader will provide you with insight into panel fabrication process while giving you the concrete knowledge applicable in this always evolving industry. This will happen in an environment that stimulates the operations of a real team that creates Shop Drawings.

physical-life-science

immuno-oncology, research-development, molecular-biology, cell-gene-therapy, industry-insights, cellular-immunotherapy

Revolutionizing Cancer Treatment: Innovative Cellular Immunotherapy Strategies

Urjita Tendolkar

and 1 more

Learn about the current landscape of cell-based cancer immunotherapies and how to propose an innovative immunotherapy approach that addresses an unmet patient need.

Molecular Biology Fellow

Cell-based immunotherapy is a rapidly evolving field that has revolutionized cancer treatment. In this project, you will have the opportunity to propose a theoretical cell-based immunotherapy candidate after reviewing the current industry trends. Under the guidance of an experienced industry specialist, you will learn fundamental concepts and processes relevant to the development of cell-based immunotherapy products. This is an excellent opportunity for early researchers to delve into the science behind cell-based immunotherapies and get exposure to relevant skills crucial for research-based roles in this field.

business

yield-curve-construction, fixed-income-analysis, interest-rates, python

Bootstrapping a Treasury Yield Curve

Vinay Bharath

and 1 more

Master the method to derive precise interest rates for different maturities by leveraging financial modelling techniques.

Finance Fellow

In this Finance Modeling Project, you'll step into the shoes of a Quantitative Analyst and construct a Treasury Yield Curve from scratch. Under the supervision of an experienced industry expert, you'll analyze market data and implement a mathematical model in Python to estimate term structures of interest rates. You'll become familiar with industry tools and methodologies for data manipulation and bootstrapping techniques for yield curve construction. All this will provide invaluable hands-on experience crucial for entry-level roles in finance, where proficiency in quantitative modeling and data analysis is highly valued.

business

finance, accounting, microsoft-excel, financial-planning

Build a Budget for an Early-Stage Startup

Fernando Lemus

and 1 more

Learn how to build in Excel an operational and capital expenditure budget for a tech startup.

Finance Fellow

Wise financial planning is crucial for the success of any business; it becomes especially important for startups that have ambitious growth goals and limited resources. In this Build Project, you'll wear the hat of a Financial Analyst and build a full-year budget that allows a fictional startup to understand its expenses and how much capital is needed to cover all business costs. You will create in Microsoft Excel a budget for employees’ salaries & benefits using dynamic formulas. Also, you’ll create a budget for professional service fees. Under the supervision of an experienced Build Fellow, you'll learn best practices in Financial Planning, specifics of operational and capital expenditure budgeting, and how to use Excel to create solid forecasting schedules. All this will happen in an environment that simulates the operations of a real Financial Planning & Analysis team.

engineering

ipsc-derived-cell-therapy, process-development, bioreactor, flow-cytometry

Process Development: Driving Cell Therapy from Research to Market

Claire Wang

and 1 more

Exploring stem cell therapy with a focus on bioreactors and bioassays used for developing a scalable cell differentiation process.

Biomedical Engineering Fellow

Cell therapy refers to the transplantation of autologous or allogeneic cells into patients to treat diseases or repair damaged tissues. However, the gap between research-scale proof of concept and clinical patient doses is significant and multifaceted. This build project aims to explore key aspects of bridging the gap between R&D and clinical application in stem cell therapy, focusing on scalable/automated cell differentiation process development and cell-based analytical techniques.

You will delve into various types of bioreactors and close-system cell processing instruments, get exposed to different analytical techniques for cell phenotyping and drug efficacy assessment, and conduct an experimental proposal using the design of experiment (DoE) concept. The project will also introduce the drug commercialization process from the perspective of CMC (chemistry, manufacturing, controls) team. You will draft master batch records and raw material risk assessments, documents required for ensuring the drug consistent productivity and quality. This comprehensive project will equip you with practical skills in designing and scaling-up cell differentiation processes, applying advanced cell-based analytical techniques, and preparing documents related to therapeutics safety and regulatory compliance.

business

venture-capital, valuation-techniques, startups, entrepreneurship, portfolio-management

Venture Fund Investing: Aligning Founders and Institutional Investors

Nadia Koritareva

and 1 more

Develop an understanding of the fundamental principles that drive Venture Capital fund investing and get insights into ways to bridge the incentives gap between entrepreneurs and institutional investors.

Finance Fellow

Innovation is powered by funding yet the relationship between startup founders and investors is often marked by misaligned incentives and conflicting interests. Receiving funding from reputable Venture Capital (VC) firms is a strong positive signal of success for any entrepreneur, yet many founders could benefit from gaining a deeper understanding of what institutional VC investors look for when identifying their next big investment opportunity.

In this Build Project, you will put yourself in the position of a private institutional investor and analyze the performance factors of a successful venture portfolio, practice negotiating a term sheet, and develop an investment memo pitching a compelling startup investment opportunity to an Investment Committee. With the guidance of a professional with private institutional investing experience, you will calculate a venture portfolio’s performance metrics and practice identifying and pitching startup investments. You will master the fundamentals of key startup valuation metrics and portfolio management basics such as calculating pre-/post-money valuations, portfolio performance metrics, and others. This project will stimulate the operations of a venture capital firm and provide holistic insights into the skills both venture investors and founders need for success in the competitive venture ecosystem.

physical-life-science

gene-editing, gene-therapy, next-generation-sequencing, assay-development, data-analysis

Deep Insight with Novel Next Generation Sequencing Assay

Malvenderjit Jagjit Singh

and 1 more

Strategize and spearhead the development of an assay aimed at determining the therapeutic potential for curing genetic disorders by leveraging novel generation sequencing approaches

Molecular Biology Fellow

RNA-seq has been selected as one of the most reliable assays in biotech research for studying gene expression level. In fact, this assay has emerged as a widely used technique for quantifying all gene expression levels. In this Build Project, you’ll imagine you assume the role of a research associate for a well-known company. They have decided to assign you the task of on boarding this assay with the purpose of investigating gene expression levels within the context of assessing the genetic tool your company has developed as part of curing genetic disorders. You will be exposed to common therapeutic approaches being conducted at molecular level and will dive deeper into different next generation sequencing technologies. These experiences represent the daily task of a research associate in the biotech industry and will be a good learning curve as part of your career development.

engineering

electrical-engineering, pysyst-simulation, engineering-project-finance-modeling, electric-load-and-power-flow-analysis, engineering-project-development

Developing Renewable Energy Project using Simulation Tools

Harshvardhan Gupta

and 1 more

Develop a project proposal that includes PVsyst and PVWatts simulation tools for plant sizing and energy calculations, along with Excel models for project financing.

Electrical Engineering Fellow

The need of the hour is to transition over to clean renewable energy for our electricity demand. With the climate change moving to an irreversible tipping point, both state and federal governments along with international authorities have introduced policies (administrative and monetary) to support the building and operations of renewable energy power plants. This opens many entry-level opportunities for firms that build, own, and operate these plants and are in constant need of engineers to support their mission and vision.

In this Build Project, you’ll wear the hat of an electrical engineer and develop and present a utility scale power plant project proposal. Under the supervision of an experienced industry expert, you’ll run simulations on the project’s electrical output, showcasing the project’s electrical power and energy calculations, and would also provide cost and financing models. You’ll become familiar with industry tools like PVSyst, PVWatts, and Microsoft Excel, for project cost and finance. All this will happen in an environment that simulates the operations of a real electrical engineering project development team.

business

market-research, international-marketing, business-management, performance-marketing

Perform Market Research for a Global E-commerce Tech Company

Jessy Dienemann

and 1 more

Analyze and interpret performance marketing and consumer behavior trends to help global companies make international expansion decisions.

Market Research Fellow

"When the economy goes south, the ad market is the first thing to go." While most business sayings should be taken with a grain of salt, this one has proven to be particularly true in recent years. In the midst of economic downturns, global pandemics and the resulting change in consumer behavior, businesses all over the world have been struggling to identify new and creative ways of efficiently engaging and acquiring net new customers at a profit.

In this Build Project, you’ll wear the hat of a Customer Success Manager and perform an opportunity analysis to determine which geographical markets a client should invest in. Under the supervision of an experienced Build Fellow, you’ll research customer behavior in various European markets, conduct a cohesive customer data analysis and create forecasts for expansion opportunities. You’ll become familiar with data analysis tools in Excel and business pitch techniques.

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business, law

legal

Enhance Your Business Savvy with Legal Contracts and Templates

Louis Weston

and 1 more

Evaluate key contract elements across various work scenarios and collaborate on crafting contract templates.

Law Fellow

Contracts are a part of everyone’s business experience. Whether you are founding your own corporation or working as an employee, you will see more than one contract in your work life. It is important to know what to look for, to know how to use them, and that you are not daunted by them. This Build Project will show you how to analyze common business contracts. With guidance from an entrepreneur with previous Legal Counsel experience, you will also develop the tools you need to review and assess contracts through the utilization of templates.

This project is for everyone. Are you an engineer wanting to start your own company, a communications major signing on to work for an organization, or a business student interested in closing your first business deal? This project will give you the skills you need to assess contracts. Your signature means a lot, so sign up for this groundbreaking project today!

physical-life-science

gene-editing, gene-therapy, biotechnology, biological-sciences, molecular-biology

Unlocking the Genome: Exploring CRISPR-Cas9 and Genotoxicity Concerns

Lavanya Venkatesan

and 1 more

Exploring Gene Therapy and Genome Editing Technologies with a Focus on CRISPR-Cas9 Mechanism, Ethical Considerations, and Genotoxicity Studies

Biotechnology Fellow

This project aims to explore key aspects of gene editing and gene therapy, focusing on current techniques, historical evolution, and the associated challenges. You will delve into the mechanisms and applications of gene editing technologies, understand how they have evolved from early experiments to sophisticated tools used in modern biotechnology and medicine. Utilizing bioinformatics tools, you will conduct an analysis to understand disease modalities, interpreting genomic data to identify and characterize structural variants, and assessing their potential impact on gene function and disease progression.

The project will also investigate genomic instability and off-target effects that can arise from gene editing, emphasizing their implications for therapeutic safety and efficacy. Additionally, you will explore the role of bioinformatics as a powerful tool for deciphering disease modalities, leveraging computational approaches to analyze genomic data and understand disease mechanisms at a molecular level.

Through this comprehensive exploration, this Build Project seeks to equip you with a deep understanding of the complexities and potentials of gene editing technologies in healthcare and biotechnology. You will produce a report about the evolution and current state of gene editing techniques, including a historical overview of gene therapy. It will also cover the mechanisms of genomic instability and off-target effects resulting from gene editing, providing insights into their implications for therapeutic safety and efficacy.

physical-life-science

biotechnology, chemical-engineering, bioprocess-development, microbiology, biochemical-engineering

Industrial Fermentation for Next Gen Sustainable Bioproducts

Priya Sengupta

and 1 more

Understand the principles of industrial fermentation and how it is crucial to develop the next generation of bio-based cleaner and greener fuels and consumer products. Gain valuable insights in biomanufacturing and propose a roadmap at the end of the build project for bio-ethanol production.

Chemical Engineering Fellow

Industrial fermentation plays a significant role in reaching the U.S ambitious net-zero emissions economy by 2050 by enabling production of sustainable alternative to fuels and chemicals to reduce greenhouse gas emissions. The industry needs qualified scientists, associate scientists, research associates and engineers now more than ever.

In this Build Project, you will wear the hat of a Fermentation Scientist and develop a roadmap for bio-ethanol production using industrial fermentation. Under the supervision of an experienced industry expert, you will visualize various fermentation process parameters, understand the trends over time, and calculate metrics to identify the areas of improvement to increase key performance metrics like yield and productivity to make a process more economic and profitable. You will become familiar with different fermentation types, equipment, culture media, microbes etc. for different end applications. All this will happen in an environment that simulates the operations of a real bioprocess development team.

physical-life-science

drug-discovery, enzyme-inhibition, virtual-screening, molecular-docking, pharmacokinetics, admet-properties

Virtual Screening for Enzyme Inhibitors in Drug Design

Rohan Kumbhare

and 1 more

Acquire proficiency in virtual screening to expedite the identification of potential enzyme inhibitors.

Biochemistry Fellow

In this project, students will tackle the exciting challenge of virtual enzyme inhibitor screening for drug discovery. Their task is to navigate through vast public databases, select a target enzyme, and design potential inhibitors using computational tools. Through hands-on virtual experiments, students will analyze docking results, predict ADMET properties, and ultimately identify promising drug candidates. By mastering these skills, students will be well-equipped for entry-level roles in the pharmaceutical industry, where the ability to leverage computational tools for drug discovery is highly valued and in demand today.

business

portfolio-management, financial-data-analysis, capital-markets, quantitative-analysis, modern-portfolio-theory

Construct an Optimization Model for an Investment Portfolio

Minh Le

and 1 more

Learn how to structure and create an optimization model and efficient frontier for a portfolio.

Finance Fellow

The concept of the frontier forms the basis of portfolio theory, which pertains to how investors seek to build a portfolio that maximizes expected returns while managing a certain level of risk. It aids investors in comprehending the risks and rewards within their portfolios, assessing how they stack up against the most efficient array of portfolios. In the finance field, you're likely to come across discussions on the efficient frontier in finance research papers or on financial news channels like Bloomberg or CNBC. Are you interested in discovering how to create a frontier from scratch and understanding its advantages and limitations? Would you like to delve into the fundamentals of portfolio management? If so, this project is perfect for you.

physical-life-science

medical-devices, regulatory-approvals, quality-management-systems, regulatory-compliance

Navigating Regulatory and Compliance Frameworks for Medical Devices

Hiral Vora

and 1 more

The regulatory environment for medical devices is designed to balance the need for innovation while ensuring patient safety. Compliance with these regulations requires a thorough understanding of the specific requirements of each market, and diligent adherence to quality standards. As technology advances, regulatory frameworks continue to evolve, necessitating adaptability from manufacturers. This project provides a comprehensive understanding of the regulatory environment governing medical devices.

Regulatory Affairs Fellow

In this Build Project, you'll step into the role of a Regulatory Affairs Specialist and tackle the challenge of navigating the complex and variable regulations governing medical devices. Working under the guidance of an experienced industry expert, you'll develop a regulatory strategy document that addresses the nuances of regulations across different countries. Through this project, you'll become proficient in interpreting guidelines and ensuring compliance, gaining valuable skills essential for success in the medical device industry. You'll also gain insights into maintaining consistent adherence to quality management systems, a crucial aspect of any medical device company's operations.

engineering

design-for-manufacturing, failure-mode-effect-analysis, root-cause-analysis, gd-t, bill-of-materials, fishbone-diagrams, control-charts

Reconstruction of Consumer Products Using Engineering Design Principles

Pranav Meshram

and 1 more

Redesign a consumer appliance and validate it for mass-production, reliability, quality, and safety. Optimize the design by using economic decision making. The project is designed to aid mechanical/ manufacturing engineering students. But the nature of the project makes it accessible to all students interested in the topic.

Mechanical Engineering Fellow

Mass-produced products are often designed to be manufactured quickly and in a cost-effective process. The traditional design of a product leads to tradeoffs in quality, safety, and reliability. In this Build Project, students will redesign 3 popular consumer products using basic and advanced engineering design principles. Students will identify problems and use TRIZ, Morphological charts, Biomimicry, data driven methods, etc. to modify the existing product.

Students will also perform DFMEA, PFMEA and follow standard industry guidelines to reach an economically feasible solution. During this project, you will learn engineering failure modes, causes and effects, perform Root cause analysis, prepare fishbone charts and use basic cost analysis for all consumer products. The tools used during this project are a staple of the manufacturing industry and will provide a great boost to students when they are showcased while working on a project.

business

data-analysis, marketing, influencers, b2b-marketing, social-media

Understanding TikTok Addiction and Its Marketing Data

Anzhe Li

and 1 more

In this project, we delve into the world of TikTok marketing to understand how influencers and advertisement work for real-life business.

Marketing Statistician Fellow

Marketing is all about ideas and numbers. In this project, we combine them both. We will first get to know what companies want when it comes to social media marketing campaigns, and how to impress them and get their budget, then we will investigate how to deliver a good result. We will be talking about influencer marketing, content marketing, data gathering, data analysis, business negotiations, platform relation management, and much more. All the project and material you use came directly from our previous for-profit projects. At the end of the project, I will have available internship opportunities for students to apply for.

business

market-research, data-analysis, trend-analysis

Run User Research and Propose App Features to Develop

Akhil Ambani

and 1 more

Gather market data through surveys and focus group and prepare recommendations on how Fizz can launch new app features.

Market Research Fellow

Knowing how to conduct a market research is a very valuable skill for anyone who plans to work in the business industry, no matter what role you want to play. In this Build Project, you'll wear the hat of a Market Research Analyst and provide recommendations on how Fizz can enter the Online Marketplace app space specifically for Gen Z users. Under the supervision of an experienced Build Fellow, you'll collect primary data using market research surveys and focus groups to understand the needs and wants of the customer base. You'll use secondary data like market reports from Statista to evaluate the importance of the trends emerged through the survey analysis. You'll become familiar with data collection, data analysis and trend spotting – and how these tasks can be performed in tools like Excel and Tableau. All this will happen in an environment that simulates the operations of a real Market Research and Analysis team.

business

financial-modeling, investments, valuation-techniques

Pitch a Stock Idea to Invest in Technology

Chi Tsai

and 1 more

Create financial projections and conduct fundamental research of a tech company for fund manager.

Finance Fellow

In this project, you'll wear the hat of equity research analyst, and pitch a stock idea with compelling thesis and financial projects. Under the supervision of an experienced Project Leader, you'll conduct fundamental research and financial modeling to support your stock idea. You'll become familiar with financial modeling and valuation techniques like financial statements including income statement, balance sheet and cash flow statement. All this will happen in an environment that simulates the operations of a real equity research team.

business

python, financial-modeling, options

Develop a Tail Hedge Strategy with S&P 500

Nan Xie

and 1 more

Use Python and SQL to analyze performance of investment strategies and recommend the optimal strategy for minimizing extreme loss from market downturn.

Finance Fellow

Under the tangled global impacts from all directions, the turbulence of the current financial market makes it hard to predict and invest. At this moment, studying tail risk (known as the extreme loss from an asset or portfolio and represented at the left tail of the return distribution) and designing tail hedge strategies has become more critical to protect against severe market distress. In this project, you'll wear the hat of Financial Engineer and study tail hedge strategies as potential investment models for controlling significant drawdown risks. Under the supervision of an experienced Build Fellow, you'll construct, implement and measure the performance of tail hedge strategies empirically using more than 15 years of index and option data. You'll also formulate your own opinion on the strategies’ behavior for the future potential market move and provide cost-effective recommendations for clients. You will use Pandas, Numpy and Matplotlib Python libraries to analyze strategies and build your own functions on selecting, exiting and entering option positions.

business

brand-management, commercial-strategy, market-research, sales

Sell Anything! Creating a Winning 360 Marketing Strategy

Caroline Chong

and 1 more

Develop an end-to-end, strategic roadmap for a new product launch.

Market Research Fellow

It is virtually impossible to successfully and efficiently sell a product, service, concept or even idea, without a clear strategy. With all the noise and continuously emerging competition, for any budding entrepreneur, this is more critical now than ever. In this Build Project, you’ll wear the hat of a Marketing Director and design a blueprint for success for a new product launch. This unique experience will give you the opportunity to step into the shoes of a senior leader and help you understand the ‘why’ and ‘what’ vs. the ‘how,’ which is where junior roles are mostly focused.

Don’t worry! You will not be on your own. Under the supervision of an experienced industry expert, you will devise a bottom-up marketing strategy, starting from the overarching big idea, derived from insights, through to the plan, execution and tracking. You’ll become familiar with market research, commercial strategy and marketing & media tactics. All of this will happen in an environment that simulates the operations for a real team and your project leader will support you through the process.

business, engineering

architectural-design-and-documentation, building-information-modeling-bim, archicad, visualization

Envision a Room of One’s Own via ArchiCAD

Lu Yu

and 1 more

Visualize a simple residential project with Building Information Modeling (BIM) software-generated plans, sections, and 3D views.

Architecture Fellow

Building Information Modeling (BIM) is a must-have skill for Architecture professionals as it provides a comprehensive and efficient way to design and document. It streamlines communication between different disciplines and facilitates the project delivery process in a market where fast-tracking has become a norm.

In this Build Project, you will design a simple residential project and generate schematic drawings using BIM software. The program will equip you with entry-level skills in the Architecture industry such as making design decisions and creating graphic representation.

engineering

mechanical-engineering, product-design, medical-devices

Propose a Design of a Novel Medical Device

Kishan Koradiya

and 1 more

Use CAD and industrial best practices to design a simple medical device of your choice.

Mechanical Engineering Fellow

Every year, there are thousands of new medical devices created to improve the lives of patients across the globe. The demand for competent engineers is on the rise, and it's crucial that they follow the best practices for developing effective and safe products. In this Build Project, you'll wear the hat of a Product Design Engineer and propose a simple device that solves a health problem of your choice (or propose a modification to an already existing device to improve any of its functions). Under the supervision of an experienced Build Fellow, you'll learn how to follow the industry guidelines for designing medical devices. You'll define User Needs, create Product Specifications, and finally prepare a 3D CAD model of your solution. All this will happen in an environment that simulates the operations of a real product development team.

engineering

medical-devices, cad, bioengineering, design, product-life-cycle

Prepare a Conceptual Design for a Medical Device (with Laborie Medical Technologies)

Len Magara

and 1 more

Use Biodesign principles & CAD to create a concept of a medical device that is user-friendly and provides enhanced patient comfort.

Biomedical Engineering Fellow

Many patients are afraid of invasive procedures required for medical diagnosis – to the point that they avoid visiting doctors. Because of that, patients miss an opportunity to discover a disease at an early stage, when it's more curable. So it's important for medical professionals to create devices that are not only effective, but comfortable and non-invasive. In this Build Project, you'll wear the hat of a Design Engineer and prepare a conceptual design for a device that improves patient experience in urodynamics testing and diagnosis focused on alternative test apparatus for a mechanical uroflow. Under the supervision of an experienced Project Leader, you’ll apply bio-mechanical design principles and use CAD software like SolidWorks to visualize your concept for a device that better meets patient's needs. All this will happen in an environment that simulates the operations of a real medical device development team.

engineering

robotics, mechatronics-engineering, python, ros2, software-development

Control a Robot's Navigation Through a Warehouse

Noé Fontana

and 1 more

Use Python to plan and control paths for an autonomous mobile robot used to unload containers in a warehouse.

Mechatronics Engineering Fellow

Increasing efficiency of robot movements is a constant battle that people in Mechatronics are fighting daily. In this Build Project, you’ll wear the hat of Robotics Mechatronics Engineer and enable a robot to navigate autonomously at dock doors in a simulated warehouse. Under the supervision of an experienced Build Fellow, you'll use Python to implement trajectories planning and following algorithms to allow an autonomous mobile robot to navigate. You’ll become familiar with the state-of-the-art ROS2 (Robot Operating System 2) and testing in simulation. The implemented solution will reflect current industry best practices.