Your application

Please complete the following fields to be considered for this project.

Please fill in this required field.
Please fill in this required field.
Please fill in this required field.
Please fill in this required field.
Please fill in this required field.
How much commitment will you have to this project?
Please select an option.
Are you available to dedicate 1-2 hours per week to the Build Project?
Please select an option.
Your application has been 
successfully submitted!
Explore more projects
Close
You already submitted an application for this project.
Explore more projects
Close
There was an error submitting your form. Please try again later or contact us.
Oops! Something went wrong while submitting the form.

This project is no longer accepting applications. Subscribe to our newsletter to be notified of new projects!

Get updates
Deep Insight with Novel Next Generation Sequencing Assay
Malvenderjit Jagjit Singh
Malvenderjit Jagjit Singh
Get updates
Register today
Apply now

Deep Insight with Novel Next Generation Sequencing Assay

Strategize and spearhead the development of an assay aimed at determining the therapeutic potential for curing genetic disorders by leveraging novel generation sequencing approaches

Register today
Apply now
Tuesdays
 at
11:00
A.M.
 ET /
8:00
A.M.
PT
8 weeks, 2-3 hours per week
Intermediate
No experience required
No experience required
Some experience required
Degree and experience required

Description

RNA-seq has been selected as one of the most reliable assays in biotech research for studying gene expression level. In fact, this assay has emerged as a widely used technique for quantifying all gene expression levels. In this Build Project, you’ll imagine you assume the role of a research associate for a well-known company. They have decided to assign you the task of on boarding this assay with the purpose of investigating gene expression levels within the context of assessing the genetic tool your company has developed as part of curing genetic disorders. You will be exposed to common therapeutic approaches being conducted at molecular level and will dive deeper into different next generation sequencing technologies. These experiences represent the daily task of a research associate in the biotech industry and will be a good learning curve as part of your career development.

Session timeline

  • Applications open
    September 5, 2024
  • Application deadline
    September 19, 2024
  • Project start date
    Week of July 8, 2024
    Week of
    October 7, 2024
  • Project end date
    Week of

What you will learn

  • Understand the importance of assay design and its impact as a therapeutic potential in curing genetic disorders.
  • Explore next generation sequencing (NGS) platforms from foundational concepts to fostering critical thinking and bioinformatics approaches.  
  • Learn to successfully perform downstream analysis for RNAseq data with different statistical methods.
Build Projects are 8-week experiences that operate on a rolling basis. Selected participants engage in weekly live workshops with a Build Fellow and 2-15 other students.

Project workshops

1
Introduction to Gene Editing: Course Overview and Technology Development
2
Assay Design Exploration – Part 1
3
Assay Design Exploration – Part 2
4
Assay Design Exploration – Part 3
5
Downstream Analysis – GitHub and Programming Language
6
Downstream Analysis – RNAseq Dataset (Part 1)
7
Downstream Analysis – RNAseq Dataset (Part 1 - Cont'd)
8
Downstream Analysis – RNAseq Dataset (Part 2) & Closing Thoughts

Prerequisites

  • Strong background in molecular biology, including having a good understanding of the central dogma of biology (e.g. transcription and translation).
  • Sufficient level of molecular biology lab experience and techniques including DNA/RNA extraction and PCR amplification to further propagate their understanding in next generation sequencing approaches.
  • Show a strong commitment for continuous learning and professional development by staying abreast with challenges that require problem-solving and technical expertise in next generation sequencing methods.
  • Familiarity in gene editing technologies, like CRISPR-Cas9 technologies, with their underlying principles and applications in therapeutic approaches.

Sign up today

Get access to all of our Build projects, including this one, by creating your Build account!

Register today
Log in

Apply to

Malvenderjit

's project today!

Get started by submitting your application.

Apply now

Stay updated!

Subscribe to our newsletter to be notified when projects reopen!

Please fill in this required field.
By clicking “Subscribe” you agree to our Terms of Services and Privacy Policy.

Thanks for subscribing!

We'll notify you when projects reopen. In the meantime, you can explore our resources and learn more about our Fellows.

Discover our articles
There was an error submitting your form. Please try again later or contact us.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
About the expert

Malven, a Molecular Biology Fellow based in Boston, works as a research associate at Tessera, where he focuses on novel assay design and sequencing technologies. Originally from Malaysia, he moved to the United States in 2018 to pursue his undergraduate studies. In his free time, Malven enjoys coding and has a passion for collecting coins and vinyl records.

Visit
Malvenderjit
's Linkedin