The Build Fellowship Hub: Newsletter

Oligonucleotides are synthetically produced biomolecules that have proven to be crucial for gene editing therapies. Biotech companies put a lot of time and effort in optimizing and developing groundbreaking analysis techniques for these molecules; purity assessment being one of the most significant ones. High performance liquid chromatography (HPLC), is one of the tools almost every research team uses to assess and characterize the constituents found in a compound. Knowing this technique becomes a very important skill even for entry-level jobs.

In this Build Project, you'll wear the hat of an Analytical Development Scientist and help optimize a method for purity/integrity assessment of oligonucleotides through RP-IP HPLC. Under the supervision of an experienced Build Fellow, you'll become proficient in navigating scientific literature and building your own conclusions and course of actions in the development of this method. You'll learn the science behind liquid chromatography and how biomolecules such as RNA behaves in such. You will also be able to appreciate role that oligonucleotides play in gene editing therapies; a rising focus for biotech companies. All this will happen in an environment that simulates the operations of a real Analytical Development team.

computing-data-science

software-development, web-development, full-stack-development

Build a Full-Stack Software Application

Karan Kwatra

and 1 more

Learn how to use PostgreSQL, Typescript, React and Vue to create a software app.

Software Development Fellow

The deliverables for this project are focused on building artifacts that you can use to showcase your work in a job application. By the end of the project, you will have built a full-stack software application that follows multi-tier architecture. You will learn about databases, back-end systems, and front-end systems. You will learn how to build an application that is extensible and complete. The application can do what you wish but must have all the relevant components. At the end of the project, you will deploy your application for anyone on the internet to view. This way, you’ll have something tangible to show recruiters for future job prospects.

computing-data-science

data-science, gender-data

Analyze a Dataset from a Critical Gender Perspective

Belise Bwiza

and 1 more

Learn gender data best practices and audit a dataset of your choice and create an improved version of the dataset analysis.

Data Science Fellow

In the field of data science, the issue of data equity is an ongoing movement that aims to promote responsible data work. The current problem with major data practices is not that the data we have is insufficient, but that it doesn’t not accurately reflect the realities of women and non-binary people. For example, the gender binary (male/female) classification system in data collection will result in omission errors that make certain people’s experiences invisible. In this Build Project, you'll wear the hat of a Data Analyst and audit data cycle practices with a gender lens. Based on it, you'll produce a data visualization project that incorporates standard visualization frameworks and gender data best practices. Under the supervision of an experienced Build Fellow, you'll uncover the flaws in current research methodologies that have led to inaccurate and incomplete data on the status of women and non-binary persons. You'll explore marginal changes that can be made to the way that we collect, analyze, and visualize gender data. You’ll become familiar with data visualization frameworks such as Tufte’s rules, Junk Chart’s trifecta, and Schwabish’s core principles, as well as such ubiquitous industry tools as Excel, R, or Tableau.  

computing-data-science

user-experience-design, product-design, web-accessibility-standards, prototyping-and-usability-testing

Design an Educational Platform for Remote Learning 

Abiola Folaranmi

and 1 more

Design an easy-to-use and visually appealing online learning platform that works well on all devices and is accessible to everyone.

Design Fellow

Since the 2020 pandemic, many industries, including education, have had to embrace digital solutions more than ever. In this project, you'll take on the role of a UX Designer to create an engaging and user-friendly e-learning platform that meets today's educational needs. Guided by an experienced Build Fellow, you'll conduct user research, design visually appealing interfaces, and implement web accessibility standards to ensure everyone can use the platform. You'll work with industry tools like Figma for prototyping and usability testing. This project will give you hands-on experience and insights into the real-world challenges of designing effective digital education solutions.

engineering

operations, project-management, climate-tech

Hydrogen Engineering Project and Supply Chain Mastery

Johannes Lamprecht

and 1 more

Develop and implement optimization models and project plans for hydrogen engineering projects, supply chains and operational processes to enhance efficiency and reduce costs in the deployment of hydrogen fuel systems for Class 8 trucks.

Operations Research Fellow

In this Build Project, you will take on the role of an Operations Research Analyst and Technical Project Manager, focusing on optimizing the supply chain and operational processes for hydrogen fuel systems and ensuring that your team of engineers is functioning at its highest level. This project is crucial for the deployment of clean fuel solutions in Class 8 trucks, aiming to reduce global emissions.

You will work on real-world challenges such as supply chain dynamics, supplier collaboration, and operational efficiency. Under the supervision of an experienced industry expert, you will develop mathematical models, perform risk assessments, and utilize data analytics to support decision-making. This project provides a unique opportunity to gain hands-on experience in a cutting-edge field that is pivotal for achieving a zero-emission future.

computing-data-science

software-development, software-engineering, computer-science

Build a Virtual Office Feature for Remote Teams

Xinyi Chen

and 1 more

Use JavaScript to develop a full-stack web application that allows remote teams to communicate via video calls. 

Computer Science Fellow

Web Development occupies a huge part of the total Software Engineer job market. For example, at Facebook, at least 30-40% of engineers are working on various Web Development projects. In this Build Project, you’ll wear the hat of a Software Engineer and develop a video call feature that can be used by remote teams. This task will allow you to develop skills across both front-end and back-end. Under the supervision of an experienced Build Fellow, you’ll become familiar with web development frontend framework/libraries such as ReactJS and Redux and web development backend framework/libraries such as NodeJS. You’ll also get hands-on experience in using basic network concepts such as WebRTC and web socket, as well as using a real-time database. All this will happen in an environment that simulates the operations of a real software engineer team. 

business

investments, venture-capital, finance, economics, business, blockchain

Create an Investment Memo for a Tech Startup

Rebecca Jovicevic

and 1 more

Provide a recommendations to a Venture Capital firm whether to invest in a technical startup or not. 

Finance Fellow

By the end of the project, students will have produced an investment memo report in the form of a PDF file. The report will include analysis of the industry the startup operates in, a competitive landscape and a capital recommendation. In the final project session, they will present their results to the Project Leader.

computing-data-science

ms-sql-server, c, javascript, web-development, net

Web Application for Flexible Data Visualization

Pavlo Tarasenko

and 1 more

Use MS SQL Server, C# and JavaScript to develop a small web app that presents and manipulates data within a browser.

Computer Science Fellow

In today's world, each web application works with data, displays large amounts of data, and processes it efficiently. The most convenient way to present this data is often in the form of tables. This Build Project challenges participants to take on the role of a Software Developer and build a small web application that presents and manipulates data within a browser. Using MS SQL Server, C#, and JavaScript, participants will create an interactive and user-friendly application. Under the supervision of an experienced Build Fellow, they will learn to handle data storage, server-side logic, and client-side scripting to deliver a seamless web experience. The challenge includes working with databases, coding dynamic web pages, and implementing data manipulation techniques to ensure the application meets user needs. Participants will become familiar with industry-standard tools and methodologies in web development. This hands-on experience will provide valuable skills applicable to entry-level jobs in software development and web engineering.

physical-life-science

molecular-biology, biotechnology, biopharmaceuticals

Identify the Potential Applications of Spatial Genomics

Yi Sun

and 1 more

Analyze the technology advancements in the spatial genomics field and explore their potential industry applications.

Molecular Biology Fellow

Spatial transcriptomics, acknowledged as Method of the Year by Nature Methods in 2020, is poised to bring transformative changes across diverse domains such as biological research, pathology, diagnostics, drug discovery, and therapeutics. In this Build Project, you will wear the hat of a Research Associate and perform a comprehensive case study to demonstrate the potential applications of spatial genomics in understanding health and disease. Under the supervision of an experienced Molecular Biology Scientist, you will conduct literature research to identify the potential applicable areas of spatial genomics. You will gain an in-depth understanding of molecular biology tools, such as FISH, next-generation sequencing, and spatial omics technologies, and how they can be utilized in a real R&D team in the biotech industry.

engineering

biotechnology, chemical-engineering, automation

Propose a Design of an Automated System to Control a Bioreactor

Truyen Le

and 1 more

Create a ladder logic program that automatically controls the operations of a bioreactor.

Chemical Engineering Fellow

In biotech industry, bioreactors are essential for producing various products like pharmaceuticals, enzymes, biochemicals, and more through biological processes such as fermentation. An automated control system optimizes and regulates critical parameters (temperature, pH, agitation, aeration, etc.), that are necessary for the growth and productivity of microorganisms within the bioreactor. In this Build Project, you'll wear the hat of Process Development Engineer and design an automated control system for a bioreactor. Under the supervision of an experienced Build Fellow, you'll learn how to create a ladder logic program to monitor and control various parameters for optimal growth conditions inside a bioreactor. All this will happen in an environment that simulates the operations of a real DSP team. 

computing-data-science

full-stack-development, rest-apis

Develop a Tool to Store & Share Password Securely

Bhupendra Thakur

and 1 more

Use Node.js to create APIs that allow company employees to follow the security compliance while sharing their passwords.

Software Development Fellow

In this Build Project, you'll wear the hat of a Full Stack Web Developer and develop a tool to store & securely share passwords. Under the supervision of an experienced Build Fellow, you'll write Node.js code to create the login, signup, save password, share password, list passwords APIs, and create a user interface to access the same. You’ll become familiar with Full Stack Development, REST API development, Relational Database management system, Cryptography, Reusable UI components, Glitch and Retool. All this will happen in an environment that simulates the operations of a real Full Stack Development team.

computing-data-science

software-development, web-development

Local-First Web Applications: Real-time, Offline and Collaborative

Shritesh Bhattarai

and 1 more

Build and deploy web applications where the user has ultimate control and ownership of their data.

Software Development Fellow

Almost all the apps that we use run on the cloud and store our data there. This has enabled us to collaborate in real-time among users, but we neither have control nor ownership over our data anymore. In this Build Project, we will explore the alternative by building and deploying local-first web applications. You will learn about and use Conflict-free Replicated Data Types (CRDTs), as well as real-time and offline APIs. You will also get familiar with the issues and impact of data privacy for users and businesses.

computing-data-science

software-development, artificial-intelligence, natural-language-processing, python, education

Build a Python Chatbot for EdTech Support

Deepthi Peri

and 1 more

Learn how to use Python to build an NLP Chatbot that answers EdTech support questions.

Computer Science Fellow

By the end of the Build Project, you'll prepare two Chatbots in the form of working code on GitHub repository / PRD - A very simple rule based Chatbot and a Predictive Chatbot using ML. You will also learn about how to use large language models to build an advanced Chatbot that builds upon the previous two. Your solution should have working code, emulate a real-life chatbot that can answer questions, and have a PRD that meets industry standards). In the final project session, you'll present your results to the Build Fellow in a format that mimics a job interview (so you’re ready to discuss your work in real-life interviews).

physical-life-science

biotechnology, molecular-biology, vaccines, cancer

Propose a Vaccine Candidate to Treat Cancer

Xavier Cabana-Puig

and 1 more

Analyze and build a theoretical vaccine candidate to help patients with limited treatment options and poor outcomes.

Molecular Biology Fellow

It's very beneficial for any young-career researcher to understand the whole cycle of a vaccine development. In this Build Project, you'll wear the hat of a scientist and suggest a new vaccine candidate that targets mutations in a cancer of your choice. Under the supervision of an experienced Build Fellow, you'll review existing clinical reports, decide which cancer your vaccine should target, develop a potential antigen sequence, and prepare a brief experimental plan for implementing in a biotech company. You'll become familiar with must-to-know tools like PubMed, Blast, Prism, Flowjo, and BioRender. All this will happen in an environment that simulates the operations of a real biotech team.

engineering

mechanical-engineering, automotive-engineering, electrical-engineering, advanced-driver-assistance-systems-adas, automotive-safety, automotive-testing, active-safety

Prepare a Performance Analysis of Tesla's Advanced Safety Features

Sundar Raman Nagarajan

and 1 more

Analyze the performance of Forward Collision Warning (FCW) and Automatic Emergency Braking (AEB) features of a Tesla Model 3.

Automotive Engineering Fellow

In this Build Project, you'll step into the role of an Advanced Driver Assistance Systems (ADAS) Testing Engineer. You'll be tasked with analyzing data from Forward Collision Warning (FCW) and Automatic Emergency Braking (AEB) tests conducted on the Tesla Model 3 encountering a stationary pedestrian. Your objective is to draw meaningful conclusions regarding pedestrian detection across various scenarios, FCW activation, braking efficiency, and avoidance rates. Guided by an experienced Build Fellow, you'll create spreadsheets, presentations, and reports to effectively convey your findings to the project team. Through this project, you'll gain insights into ADAS testing protocols, current research, technological advancements in ADAS, and the performance of Tesla’s FCW/AEB system. Additionally, you'll develop a comprehensive understanding of the algorithms behind Tesla’s FCW/AEB functionality.

engineering

biotechnology, biomedical-engineering, mechanical-engineering

Design a Low-Cost Healthcare Device

Zoe Jiang

and 1 more

Prepare a conceptual design for a point-of-care medical device for affordable disease detection or healthcare condition monitoring.

Mechanical Engineering Fellow

In this Build Project, you’ll wear the hat of Research Scientist and create a design concept for a medical diagnostic device of your choice (for diabetes, malaria, or cardiovascular disease). We'll use computer-aid design software to simulate and validate your design. This is a rare opportunity for students who are interested in the medical device development field as their future career. You can gain practical experience by working on a real-world project and be familiar with point-of-care testing and other biotechnologies, in an environment that simulates the operation of a real product development team.

engineering

biotechnology, immunotherapy, immunology, flow-cytometry, adoptive-cell-therapy

Analyze Flow Cytometry Panels for Cell-Based Immunotherapy

Gauri Kulkarni

and 1 more

Perform flow cytometry analysis to characterize cells used in different forms of immunotherapies and effectively visualize data using real-world examples.

Molecular Biology Fellow

Lymphocytes are important white blood cells in the immune system that invade tumors and hold potential for cancer treatment. Understanding their phenotype and functionality through flow cytometry analysis is essential for developing cell therapy drug products and these skills are crucial for building a career in the Immuno-Oncology field. In this Build Project, you will get a solid foundation in flow cytometry to independently analyze basic flow cytometry panels & generate data summaries. You will analyze at least one primary seven or eight-color flow cytometry panel to characterize lymphocytes that can exert anti-tumor activity. You'll also learn to use popular software tools like FlowJo & GraphPad Prism to analyze and visualize data.

computing-data-science

data-science, data-visualization, data-preprocessing, feature-engineering, natural-language-porcessing, machine-learning, python

Sentiment Analysis Using Machine Learning Models

Yaya Liu

and 1 more

Develop machine learning models to train computers to interpret text and predict whether a customer’s attitude is positive, negative or neutral towards a company or the service they received from the company based on text data from Twitter.

Data Science Fellow

The airline industry is more competitive than it has ever been since more and more small and low-cost carriers entered the market. In order to increase business competitiveness, companies need to constantly assess and monitor how satisfied the customers are with the company and the service the company provides, as well as identify any potential negative trends on social media.

In contrast to traditional paper-based surveys, machine learning models provide a more timesaving, economical, and reliable way to identify and quantify customers’ opinions and attitudes, especially by utilizing massive data from social media. In this Build Project, you will build machine learning models to train computer software to interpret text and predict whether a customer’s attitude is positive, negative or neutral towards the service they received from six U.S. airline companies based on text data from Twitter. You will get exposed to Exploratory Data Analysis (EDA), text preprocessing, feature engineering, data balancing, model design, development and evaluation. You'll get exposed to the daily life of a Data Scientist and learn techniques that are must-to-know for any DS professional.

engineering

additive-manufacturing, latticing, topology-optimization, optimization, fea, mechanical-design, computational-design, dfam

Design Optimization of Automative Bracket for Additive Manufacturing

Ajay Prasad

and 1 more

Optimize an automotive bracket using topology optimization and latticing for additive manufacturing.

Mechanical Engineering Fellow

Lightweighting is strategically decreasing mass while preserving overall strength and structural integrity. Additive manufacturing has created opportunities to apply new lightweighting techniques that enable you to achieve even greater mass reduction.

In today's rapidly evolving engineering landscape, additive manufacturing (AM) stands at the forefront of innovation, offering unparalleled opportunities for maximizing performance and efficiency while minimizing lead times. Companies across industries are embracing AM to push the boundaries of traditional manufacturing methods and unlock new possibilities in design optimization.

In our Build Project, you will learn the power of computational design and AM technologies to lightweight mechanical parts, mirroring the innovative approaches in real-world industry applications. Through this project, you will gain invaluable skills in computational design, material selection, and additive manufacturing, positioning them for success in the dynamic landscape of modern engineering and manufacturing roles.

business

risk-management, business-operations, risk-financing

Develop a Risk Management Plan for a Mid-Size Company

Luis Sarmiento

and 1 more

Understand the operations and business exposures to provide business risk management solutions using the Risk Management Process.

Finance Fellow

It's imperative for the survival of a company to understand the cost & opportunity of various risks and to learn how to manage them. In this Build Project, you'll wear the hat of a Chief Risk Officer / Risk Advisor and build a comprehensive risk management plan for a client. You will help that company understand their vulnerabilities and opportunities and give them your recommendation on how to manage their risk. Under the supervision of an experienced Build Fellow, you'll learn about the different risk management techniques: risk transfer, risk avoidance, risk mitigation, and risk acceptance. You will become familiar with the Risk Management and Financial methodologies like the risk management process, the financial ratios, forecasting, and the loss triangulation, in an environment that simulates the operations of a real risk management team.

engineering

biotechnology, cell-gene-therapy, biomedical-engineering, immunotherapy, bioengineering, biology

Analyze Flow Cytometry Data to Evaluate CAR-T Cytotoxicity

Srutartha Bose

and 1 more

Use FlowJo and GraphPad Prism software to perform flow cytometry analysis and statistical analysis of CAR-T cytotoxicity dataset generated in cell and gene therapy industry.

Biomedical Engineering Fellow

In this Build Project, you'll wear the hat of Research Associate and evaluate Flow Cytometry datasets generated by a Tumor Cell Killing Potency assay. Under the supervision of an experienced Build Fellow, you will statistically analyze cytotoxicity datasets to compare the performance of different drug products. This project will expose you to FlowJo and GraphPad Prism (two very popular tools in biotechnology, biomedical and pharmaceutical industries), as well as familiarize you with critical assay attributes. By completing this project, you will be able to make business-driven scientific in an environment that simulates the operations of a real Analytical Development team.

computing-data-science

software-development, cybersecurity, cloud-computing

Develop a Secure SafeAPI Web Application

Rehana Shaikh

and 1 more

Learn how to create a secure web application with reCAPTCHA integration and real-time API request analysis using Google Cloud Functions.

Software Development Fellow

In the ever-evolving landscape of cybersecurity, defending against different cyber threats is a critical challenge. This Build Project focuses on developing a secure web application with reCAPTCHA authentication and implementing a Cloud Function for real-time API request analysis. Under the guidance of an experienced Build Fellow, you will actively contribute to the project's core deliverables, gaining hands-on experience with industry tools such as Cloud Pub/Sub and Firestore. This project mirrors the operations of a real-world Security Analyst team, providing invaluable insights and practical skills for a career in cybersecurity.

computing-data-science

cybersecurity, information-security, information-technology, forensics, vulnerability-management

Prepare a Malware Analysis Report

Zeeshan Ahmed

and 1 more

Learn how to analyze malware like a Cybersecurity pro by using market-leading Cyber Forensic tools.

Cybersecurity Fellow Fellow

Malware analysis is one of the key processes in cybersecurity. Cybersecurity specialists are constantly asked to analyze suspicious files to check whether they're legitimate or malicious. In this Build Project, you'll wear the hat of Security Analyst and prepare a standard report that companies use to develop countermeasures and strategies for preventing or mitigating future attacks. Under the supervision of an experienced Build Fellow, you'll learn about different types of malware, steps of incidence response investigation, and how to use forensic tools like PEiD, ProcMon, and Wireshark. You will be exposed to the daily life of a Malware Analyst and learn the procedures and techniques that any cybersecurity specialist should know.

physical-life-science

next-generation-sequencing, target, lead-compound, molecular-biology

Apply Next Generation Sequencing Analysis for Lead Discovery

Yanling Wang

and 1 more

Use high-through put data analysis to predict candidates for pharmaceutical drug target

Biotechnology Fellow

For any bio-pharma company, selecting a promising target for drug discovery is a critical step in a very costly drug research & development process. Companies either have a special group of scientists working on target selection full-time or dedicate time to it early in the process. In this Build Project, you will wear the hat of a Data Scientist and perform target selection through the analysis of next generation sequencing data. Under the supervision of an experienced Build Fellow, you will become familiar with high-throughput database website, data download and analysis, and propose 2-3 targets for a selected disease. All this will happen in an environment that simulates the operation of a bioinformatician team.

business

healthcare-industry, life-science, drug-pricing, pharmaceutical-supply-chain

Product, Contracting, and Dollar Flow in the U.S. Healthcare Industry

Ranganath Narayanan

and 1 more

Build an overview of product, contracting, and dollar flow between key stakeholders in the U.S. healthcare industry.

Health Services Fellow

The landscape of the US healthcare industry resembles a complex and fragmented puzzle with various types of pieces. Numerous stakeholders, including healthcare providers, insurance companies, pharmaceutical manufacturers, and government agencies, contribute to a system that often appears intricate and challenging to navigate. The intricate web of regulations, varying payment structures, and the multitude of players involved can make understanding the flow of dollars, products, and contracts seem like solving a 1000-piece puzzle without edge-pieces.Imagine that a pharmaceutical organization that partners with Company X, has reached out asking for support to provide an overview of the value drivers of key stakeholders in the healthcare industry and the flow of product, dollar, and contracts between these stakeholders that they plan to use to train their salesforce new hires. This information will provide a foundation for their salesforce that will help them navigate conversations with healthcare providers, hospital administrators, and payers. You are part of the Company X team and will have to work on this challenge.

In this project, you will first describe the roles, responsibilities, and value drivers of key stakeholders in the healthcare industry including Beneficiaries, Pharmacies, Wholesalers, Payers, Providers, Manufacturers, Funders, and Pharmacy Benefit Managers, and then create a visually appealing flowchart that accurately represents the flow of product, dollar, and contracting between them. This is an opportunity for you to understand the value that each of these stakeholders provide to the healthcare system and how they co-exist to finally provide affordable and quality healthcare services to patients. After completing this project, you will get a deep understanding of the intricacies of the US healthcare industry, develop strong strategic thinking, research, and analytical skills, and improve your ability to communicate your knowledge and insights gathered in a clear, specific, and visually appealing format.

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