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Apply Next Generation Sequencing Analysis for Lead Discovery
Yanling Wang
Yanling Wang
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Apply Next Generation Sequencing Analysis for Lead Discovery

Use high-through put data analysis to predict candidates for pharmaceutical drug target

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Apply now
Wednesdays
 at
9:00
A.M.
 ET /
6:00
A.M.
PT
8 weeks, 2-3 hours per week
Intermediate
No experience required
No experience required
Some experience required
Degree and experience required

Description

For any bio-pharma company, selecting a promising target for drug discovery is a critical step in a very costly drug research & development process. Companies either have a special group of scientists working on target selection full-time or dedicate time to it early in the process. In this Build Project, you will wear the hat of a Data Scientist and perform target selection through the analysis of next generation sequencing data. Under the supervision of an experienced Build Fellow, you will become familiar with high-throughput database website, data download and analysis, and propose 2-3 targets for a selected disease. All this will happen in an environment that simulates the operation of a bioinformatician team.

Session timeline

  • Applications open
    May 27, 2024
  • Application deadline
    June 23, 2024
  • Project start date
    Week of July 8, 2024
    Week of
    July 8, 2024
  • Project end date
    Week of

What you will learn

  • Have a deep understanding of next-generation sequencing database
  • Master NGS sequencing analysis with web-based tool
  • Showcase your data analysis ability and generate your own customized NGS report

Build Projects are 8-week experiences that operate on a rolling basis. Selected participants engage in weekly live workshops with a Build Fellow and 2-15 other students.

Project workshops

1
Introductions
2
NGS for drug discovery
3
Finding genomic data
4
Decoding GEO dataset
5
NGS data analysis
6
NGS data analysis tools
7
Applying NGS analysis tools
8
Presentations

Prerequisites

  • Basic/intermediate knowledge of cell and molecular biology: you should be able to understand disease models where applicable.
  • Basic/intermediate knowledge of next generation sequencing technologies.  
  • Other prerequisites: before the project starts, you'll need to have Microsoft PowerPoint and Microsoft Teams installed on your computer.

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About the expert

Yanling is a Build Fellow specializing in biotechnologies at Open Avenues, where she works with students leading projects in molecular biology.

Yanling is a scientist at FireCyte Therapeutics where she works on exploring novel treatment strategies for neurodegenerative diseases. Yanling has over 10 years of research experience in molecular biology, focusing on obesity, fatty liver disease and immunology. Yanling holders a PhD degree in Biology, and she is applying all her expertise in the neuron-inflammatory disease.

In her own time, she likes playing badminton, hiking.

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Yanling
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