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Learn from Fellows working at cutting-edge companies across the United States.
This project aims to explore key aspects of gene editing and gene therapy, focusing on current techniques, historical evolution, and the associated challenges. You will delve into the mechanisms and applications of gene editing technologies, understand how they have evolved from early experiments to sophisticated tools used in modern biotechnology and medicine. Utilizing bioinformatics tools, you will conduct an analysis to understand disease modalities, interpreting genomic data to identify and characterize structural variants, and assessing their potential impact on gene function and disease progression.
The project will also investigate genomic instability and off-target effects that can arise from gene editing, emphasizing their implications for therapeutic safety and efficacy. Additionally, you will explore the role of bioinformatics as a powerful tool for deciphering disease modalities, leveraging computational approaches to analyze genomic data and understand disease mechanisms at a molecular level.
Through this comprehensive exploration, this Build Project seeks to equip you with a deep understanding of the complexities and potentials of gene editing technologies in healthcare and biotechnology. You will produce a report about the evolution and current state of gene editing techniques, including a historical overview of gene therapy. It will also cover the mechanisms of genomic instability and off-target effects resulting from gene editing, providing insights into their implications for therapeutic safety and efficacy.
With the US economy and population now being dominated by baby boomers (the demographic cohort born during the mid-40s and mid-60s), we face a significantly high number of individuals retiring from the workforce. In addition, we are in the middle of the biggest wealth transfer in the history of the U.S. This presents a great opportunity for individuals with skills to offer financial and investment advice.
In this Build Project, you'll wear the hat of a Financial and Investment Research Analyst. You will showcase the ability to evaluate the current makeup of the investment portfolio using the profitability/valuation ratios and risk metrics to develop and design an investment strategy to align the portfolio to the current business and economic cycle. Under the supervision of an experienced industry expert, you'll compute the various investment ratios and statistical measurements used in portfolio construction and analysis. Also, you will evaluate the stock's common types of performance measurements and intrinsic value and explain how portfolio risk is used to develop efficient frontier/portfolios. You'll become familiar with industry tools/techniques/methodologies like Modern Portfolio Theory, Capital Asset Pricing Model, Ratio Analysis, and Efficient Market Hypothesis Concepts. All this will happen in an environment that simulates the operations of a real Financial and Investment Research Analyst.
To stay relevant and profitable, companies need to constantly review their growth strategy and identify new market opportunities. Specialists who can do this work effectively are always in demand, so it's a valuable skillset to acquire. In this Build Project, you'll wear the hat of a Corporate Development Analyst and come up with a potential acquisition target (company) to analyze and present. Under the supervision of an experienced Build Fellow, you'll perform market research, financial analysis and build a dynamic valuation model in Excel. You'll become familiar with valuation methodologies like DCF, NPV and WACC. All this will happen in an environment that simulates the operations of a real Corporate Development team.
Allogenic hematopoietic stem cell transplant (HSCT) is the only cure for patients with blood, bone marrow and immune disorders. Understanding the underlying molecular biology behind HSC function, expansion, and differentiation is critical to improve cellular therapies for multiple diseases. In this Build Project, you will wear the hat of a Molecular Research Associate to perform RNA sequencing analysis and then identify relevant pathways and genes of interest in HSC functions. All this will happen in an environment that simulates the operations of a real Research team.
By the end of the 8-week project, students will develop deliverables for this project are focused on building artifacts that you can use to showcase your work in a job application. By the end of the micro-internship, you'll review an RNAseq gene pathway from human hematopoietic stem cells, perform a comparative analysis between multiple conditions, and develop gene knockout and genotyping designs. In the final project session, you'll present your results to the Project Leader in a format that mimics a job interview (so you’re ready to discuss your work in real-life interviews).
If you want to work in Commercial Real Estate, it’s beneficial for your portfolio to acquire some industry-specific experiences. In this Build Project, you'll wear the hat of an Asset Management Analyst and monitor the financial performance of an office asset within a commercial real estate portfolio in Los Angeles. The investment committee that approved the acquisition of said asset has requested a meeting to provide them with an update on market and asset performance a year into acquisition. Under the supervision of an experienced Build Fellow, you'll work on valuation and investment metrics, returns, variances in financial statements, and market fundamentals. You'll also become familiar with industry tools such as Excel, PowerPoint, Costar, and Cushman & Wakefield. All this will happen in an environment that simulates the operations of a real CRE (Commercial Real Estate) Asset Management team.
In most organizations, data is stored in hundreds or thousands of columns stored in multiple tables. With this level of complexity, it's often hard to understand the relation between tables, columns, views, and workflows. In this Build Project, you'll build a library that takes in a complicated data schema, analyzes all the existing relations, and provide a flow chart as an output to easily understand all the relations and how data flows in the system. All these skills are essential for the productive work of any specialist analyzing large datasets, and in this project, you have a chance to develop them under supervision of an experienced Project Leader.
To analyze urban patterns effectively, city planners collect extensive datasets that encompass a wide range of information, such as accidents, collisions, rule violations, congestion, and more. Understanding and interpreting these datasets is crucial for informed urban planning and development. Visualization plays a pivotal role in this process, serving as a powerful tool to capture trends, narrate stories, and identify the underlying causes of urban issues. It also aids in devising effective solutions to mitigate these problems.
In this Build Project, you will take on the role of an Urban Planner, focusing on visualizing city public datasets. Under the guidance of an experienced Build Fellow, you will develop a cutting-edge application using WebGL technology. This application will analyze publicly available urban data, process it, and present it in a user-friendly format. The goal is to create a tool that not only helps city planners and officials understand urban patterns and issues but also engages and informs the public. Your work will contribute to making data-driven decisions for improving urban mobility and enhancing the overall quality of life in the city.
Immunofluorescence is a widely used tool in the visualization of protein and biomolecules within fixed cultured cells (immunocytochemistry) or preserved and sectioned patient or animal tissue (immunohistochemistry). Fluorescent immunostaining is a reliable confirmation technique used across scientific disciplines both in academia and industry. However, without extremely expensive and proprietary software, analysis and interpretation of this data can be complicated and time-consuming. In this Build Project, you'll wear the hat of a scientist or engineer and build a pipeline capable of delivering high-throughput single cell data from immunofluorescent images. Under the supervision of an experienced Build Fellow, you'll design a segmentation workflow and analyze data. You'll become familiar with industry tools like Cell Profiler and ImageJ. All this will happen in an environment that simulates the operations of a real biotech team.
Applying principles of Business, Finance, and Management, in this Build Project you will gather and analyze macroeconomic data, perform competition analysis, use financial modeling to project scenarios, and support strategic decisions for a high-tech software development company offering a game-changing technology in multiple markets ranging from banking, telecom, online services, and pharma. This will be an opportunity for students to experience contributing to a real-world project involving AI, Biometrics, and data privacy.
Lightweighting is strategically decreasing mass while preserving overall strength and structural integrity. Additive manufacturing has created opportunities to apply new lightweighting techniques that enable you to achieve even greater mass reduction.
In today's rapidly evolving engineering landscape, additive manufacturing (AM) stands at the forefront of innovation, offering unparalleled opportunities for maximizing performance and efficiency while minimizing lead times. Companies across industries are embracing AM to push the boundaries of traditional manufacturing methods and unlock new possibilities in design optimization.
In our Build Project, you will learn the power of computational design and AM technologies to lightweight mechanical parts, mirroring the innovative approaches in real-world industry applications. Through this project, you will gain invaluable skills in computational design, material selection, and additive manufacturing, positioning them for success in the dynamic landscape of modern engineering and manufacturing roles.
In biotech industry, bioreactors are essential for producing various products like pharmaceuticals, enzymes, biochemicals, and more through biological processes such as fermentation. An automated control system optimizes and regulates critical parameters (temperature, pH, agitation, aeration, etc.), that are necessary for the growth and productivity of microorganisms within the bioreactor. In this Build Project, you'll wear the hat of Process Development Engineer and design an automated control system for a bioreactor. Under the supervision of an experienced Build Fellow, you'll learn how to create a ladder logic program to monitor and control various parameters for optimal growth conditions inside a bioreactor. All this will happen in an environment that simulates the operations of a real DSP team.
Mass-produced products are often designed to be manufactured quickly and in a cost-effective process. The traditional design of a product leads to tradeoffs in quality, safety, and reliability. In this Build Project, students will redesign 3 popular consumer products using basic and advanced engineering design principles. Students will identify problems and use TRIZ, Morphological charts, Biomimicry, data driven methods, etc. to modify the existing product.
Students will also perform DFMEA, PFMEA and follow standard industry guidelines to reach an economically feasible solution. During this project, you will learn engineering failure modes, causes and effects, perform Root cause analysis, prepare fishbone charts and use basic cost analysis for all consumer products. The tools used during this project are a staple of the manufacturing industry and will provide a great boost to students when they are showcased while working on a project.
In this project, students will tackle the exciting challenge of virtual enzyme inhibitor screening for drug discovery. Their task is to navigate through vast public databases, select a target enzyme, and design potential inhibitors using computational tools. Through hands-on virtual experiments, students will analyze docking results, predict ADMET properties, and ultimately identify promising drug candidates. By mastering these skills, students will be well-equipped for entry-level roles in the pharmaceutical industry, where the ability to leverage computational tools for drug discovery is highly valued and in demand today.
Industrial fermentation plays a significant role in reaching the U.S ambitious net-zero emissions economy by 2050 by enabling production of sustainable alternative to fuels and chemicals to reduce greenhouse gas emissions. The industry needs qualified scientists, associate scientists, research associates and engineers now more than ever.
In this Build Project, you will wear the hat of a Fermentation Scientist and develop a roadmap for bio-ethanol production using industrial fermentation. Under the supervision of an experienced industry expert, you will visualize various fermentation process parameters, understand the trends over time, and calculate metrics to identify the areas of improvement to increase key performance metrics like yield and productivity to make a process more economic and profitable. You will become familiar with different fermentation types, equipment, culture media, microbes etc. for different end applications. All this will happen in an environment that simulates the operations of a real bioprocess development team.
Wise financial planning is crucial for the success of any business; it becomes especially important for startups that have ambitious growth goals and limited resources. In this Build Project, you'll wear the hat of a Financial Analyst and build a full-year budget that allows a fictional startup to understand its expenses and how much capital is needed to cover all business costs. You will create in Microsoft Excel a budget for employees’ salaries & benefits using dynamic formulas. Also, you’ll create a budget for professional service fees. Under the supervision of an experienced Build Fellow, you'll learn best practices in Financial Planning, specifics of operational and capital expenditure budgeting, and how to use Excel to create solid forecasting schedules. All this will happen in an environment that simulates the operations of a real Financial Planning & Analysis team.
Cell-based immunotherapy is a rapidly evolving field that has revolutionized cancer treatment. In this project, you will have the opportunity to propose a theoretical cell-based immunotherapy candidate after reviewing the current industry trends. Under the guidance of an experienced industry specialist, you will learn fundamental concepts and processes relevant to the development of cell-based immunotherapy products. This is an excellent opportunity for early researchers to delve into the science behind cell-based immunotherapies and get exposure to relevant skills crucial for research-based roles in this field.
It is virtually impossible to successfully and efficiently sell a product, service, concept or even idea, without a clear strategy. With all the noise and continuously emerging competition, for any budding entrepreneur, this is more critical now than ever. In this Build Project, you’ll wear the hat of a Marketing Director and design a blueprint for success for a new product launch. This unique experience will give you the opportunity to step into the shoes of a senior leader and help you understand the ‘why’ and ‘what’ vs. the ‘how,’ which is where junior roles are mostly focused.
Don’t worry! You will not be on your own. Under the supervision of an experienced industry expert, you will devise a bottom-up marketing strategy, starting from the overarching big idea, derived from insights, through to the plan, execution and tracking. You’ll become familiar with market research, commercial strategy and marketing & media tactics. All of this will happen in an environment that simulates the operations for a real team and your project leader will support you through the process.
In the rapidly evolving field of Augmented Reality (AR) and Virtual Reality (VR), the demand for professionals who can navigate the unique software development models and methods is high. In this Build Project, you will step into the role of an AR/VR Software Developer and develop an application that can overlay augmented content on device camera frames. Under the guidance of an industry expert, you will explore and evaluate the specifications and performance of various mobile phones in the market that can be used for real-time object inference and world-locked rendering.
You will delve into the intricacies of Simultaneous Localization and Mapping (SLAM) algorithms, which are crucial for world-locked rendering of overlay media content. Furthermore, you will identify the best methods and algorithms suited for real-time object inference and augmentation rendering to camera frames.
You will become familiar with AR/VR technologies and their unique software development cycles, using tools and methodologies like Unity, C#, and ARCore. All this will happen in an environment that simulates the operations of a real AR/VR development team. By the end of the project, you will have a functional application that can be further expanded and improved by adding other metadata as an augmentation layer on top of camera frames.
Many patients are afraid of invasive procedures required for medical diagnosis – to the point that they avoid visiting doctors. Because of that, patients miss an opportunity to discover a disease at an early stage, when it's more curable. So it's important for medical professionals to create devices that are not only effective, but comfortable and non-invasive. In this Build Project, you'll wear the hat of a Design Engineer and prepare a conceptual design for a device that improves patient experience in urodynamics testing and diagnosis focused on alternative test apparatus for a mechanical uroflow. Under the supervision of an experienced Project Leader, you’ll apply bio-mechanical design principles and use CAD software like SolidWorks to visualize your concept for a device that better meets patient's needs. All this will happen in an environment that simulates the operations of a real medical device development team.
The concept of the frontier forms the basis of portfolio theory, which pertains to how investors seek to build a portfolio that maximizes expected returns while managing a certain level of risk. It aids investors in comprehending the risks and rewards within their portfolios, assessing how they stack up against the most efficient array of portfolios. In the finance field, you're likely to come across discussions on the efficient frontier in finance research papers or on financial news channels like Bloomberg or CNBC. Are you interested in discovering how to create a frontier from scratch and understanding its advantages and limitations? Would you like to delve into the fundamentals of portfolio management? If so, this project is perfect for you.
Contracts are a part of everyone’s business experience. Whether you are founding your own corporation or working as an employee, you will see more than one contract in your work life. It is important to know what to look for, to know how to use them, and that you are not daunted by them. This Build Project will show you how to analyze common business contracts. With guidance from an entrepreneur with previous Legal Counsel experience, you will also develop the tools you need to review and assess contracts through the utilization of templates.
This project is for everyone. Are you an engineer wanting to start your own company, a communications major signing on to work for an organization, or a business student interested in closing your first business deal? This project will give you the skills you need to assess contracts. Your signature means a lot, so sign up for this groundbreaking project today!
"When the economy goes south, the ad market is the first thing to go." While most business sayings should be taken with a grain of salt, this one has proven to be particularly true in recent years. In the midst of economic downturns, global pandemics and the resulting change in consumer behavior, businesses all over the world have been struggling to identify new and creative ways of efficiently engaging and acquiring net new customers at a profit.
In this Build Project, you’ll wear the hat of a Customer Success Manager and perform an opportunity analysis to determine which geographical markets a client should invest in. Under the supervision of an experienced Build Fellow, you’ll research customer behavior in various European markets, conduct a cohesive customer data analysis and create forecasts for expansion opportunities. You’ll become familiar with data analysis tools in Excel and business pitch techniques.
In this project, you'll wear the hat of equity research analyst, and pitch a stock idea with compelling thesis and financial projects. Under the supervision of an experienced Project Leader, you'll conduct fundamental research and financial modeling to support your stock idea. You'll become familiar with financial modeling and valuation techniques like financial statements including income statement, balance sheet and cash flow statement. All this will happen in an environment that simulates the operations of a real equity research team.
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